Three buddies wake up from a bachelor party in Las Vegas, with no memory of the previous night and the bachelor missing. They make their way around the city in order to find their friend before his wedding. Three of them later wake up with a hangover, unable to recollect what exactly happened. With the villa in a wreck, they find that they have a baby in the closet; a grown tiger in the bathroom; Stu has a missing tooth and a hooker for a bride, and Doug is missing.